miXED Messages in Ion Channel Modulation

miXED Messages in Ion Channel Modulation

Ion channels are modulated by multiple molecular mechanisms. In this issue of Neuron, Pietrzykowski et al. expand the mechanistic repertoire by demonstrating that ethanol-induced microRNA can modulate the pattern of mRNA splice variants from which BK potassium channels are constructed. Because BK channels are important targets of ethanol, this finding has implications for mechanisms of ethanol ...

Mixed messages

Ion Channel Modulation by Photocaged Dioctanoyl PIP2

ION CHANNEL MODULATION BY PHOTOCAGED DIOCTANOYL PIP2 by Junghoon Ha, BSc. A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth University. Virginia Commonwealth University, 2009 Thesis Director: Diomedes E. Logothetis, Ph.D. Chair, Department of Physiology and Biophysics Phosphatidylinositol bisphosphate (PIP2) directly regul...

Mixed messages

plants are cloaked in hundreds of tiny projections, known as trichomes. These structures vary in function, shape, size and spacing from species to species, and it’s not known whether similar cellular differentiation programs are responsible for making trichomes in different plants. Trichomes are clearly visible in the scanning electron micrograph of a wild-type Nicotiana tabacum seedling above ...

Ion Channel Modulation in Spinal/Trigeminal Synaptic Plasticity

1 Department of Oral Physiology, School of Dentistry, Kyungpook National University, 188-1 Samduck-2, Chung-gu, Daegu 700-412, Republic of Korea 2Department of Anatomy, Histology and Embryology, Semmelweis University, Tüzoltó utca 58, Budapest 1450, Hungary 3 Department of Pharmacology, University of Colorado School of Medicine, Mail Stop 8315, 12800 E. 19th Avenue, P18-7104, Aurora, CO 80045, USA